New Data on the Dissemination of the Nipah Virus (Henipavirus. Paramyxoviridae) and Methods of its Indication and Identification

• Published in: Problemy osobo opasnyh infekcij no. 1; pp. 27 - 36
• Main Authors: Krivosheina, E. I., Kartashov, M. Yu, Thi Nhai, Tran, Naidenova, E. V.
• Format: Journal Article
• Language: English; Russian
• Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 01.05.2023
• Subjects: enzyme immunoassay (elisa); methods of indication and identification; nipah virus; polymerase chain reaction (pcr)
• ISSN: 0370-1069; 2658-719X
• DOI: 10.21055/0370-1069-2023-1-27-36

Nipah virus (Nipah virus, NiV) is a representative of the genus Henipavirus of the Paramyxoviridae family, the causative agent of a dangerous infectious disease with a wide range of clinical manifestations – from an asymptomatic (subclinical) form to severe encephalitis with fatal outcome. Despite the fact that the disease caused by this virus is registered only in the countries of Southeast Asia, the possibility of importing the pathogen to non-endemic territories is not excluded. Also, this pathogen is able to infect not only a large number of people, but also animals, causing serious diseases and significant economic damage, posing both, a medical and veterinary problem. This review presents the data available in the modern press on the structure and classification of the Nipah virus, possible cycles of its transmission, spread, methods of indication and identification in clinical and biological material, as well as the effectiveness of their use depending on the timing of the onset of the disease and available commercial diagnostic and preventive drugs.