Comparative Study of Some Physical-Chemical and Immunochemical Properties of Plague Microbe Lipopolysaccharide Preparations Obtained with the Help of Different Techniques

, and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity. Aside from that, it is demonstrated that potentially PS is the most productive molecule fragment of LPS for the construction of plague imm...

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Published inProblemy osobo opasnyh infekcij no. 3(113); pp. 50 - 53
Main Authors Polunina, T. A., Guseva, N. P., Kireev, M. N., Taranenko, T. M., Devdariani, Z. L., Zadnova, S. P., Kuznetsova, E. M., Stepanov, A. V., Klyueva, S. N., Zakharova, T. L.
Format Journal Article
LanguageEnglish
Russian
Published Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 20.06.2012
Subjects
degraded polysaccharide
lipopolysaccharide
yersinia pestis
деградированный полисахарид
липополисахарид
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Summary:, and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity. Aside from that, it is demonstrated that potentially PS is the most productive molecule fragment of LPS for the construction of plague immunodiagnostic preparation, since despite its decreased cytotoxocity PS retains identity of chemical composition and immunechemical specificity of endotoxin.
ISSN:0370-1069
2658-719X
DOI:10.21055/0370-1069-2012-3-50-53