Current Methods of Prevention of Aminoglycoside Ototoxicity in Patients with Pulmonary Tuberculosis

Contemporary publications on possible pharmaceutical treatment of ototoxic effect of aminoglycosides have been analyzed. In this respect, substances with the antioxidant effect seem to be the most promising. Their use in therapeutic doses is not accompanied by adverse reactions, and they do not inte...

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Published inTuberkulëz i bolezni lëgkikh Vol. 101; no. 3; pp. 87 - 93
Main Authors Solokha, A. A., Stavitskaya, N. V., Shvarts, Ya. Sh, Sklyuev, S. V., Tursunova, N. V.
Format Journal Article
LanguageEnglish
Published 04.07.2023
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Summary:Contemporary publications on possible pharmaceutical treatment of ototoxic effect of aminoglycosides have been analyzed. In this respect, substances with the antioxidant effect seem to be the most promising. Their use in therapeutic doses is not accompanied by adverse reactions, and they do not interfere with the antibacterial effect of anti-tuberculosis drugs. Currently, the mechanisms of the otoprotective action of various antioxidants are being studied.
ISSN:2075-1230
2542-1506
DOI:10.58838/2075-1230-2023-101-3-87-93