Dual‐Targeted Lipid Nanotherapeutic Boost for Chemo‐Immunotherapy of Cancer (Adv. Mater. 13/2022)

Immunotherapy In article number 2106350, Dan Peer and co‐workers propose a strategy to boost chemo‐immunotherapy by using a dual cell‐targeted lipid nanotherapeutic boost. With this approach, chemo‐induced immunogenic cancer cell death is increased, tumor myeloid cell is reprogrammed, and cytotoxic...

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Bibliographic Details
Published inAdvanced materials (Weinheim) Vol. 34; no. 13
Main Authors Yong, Seok‐Beom, Ramishetti, Srinivas, Goldsmith, Meir, Diesendruck, Yael, Hazan‐Halevy, Inbal, Chatterjee, Sushmita, Somu Naidu, Gonna, Ezra, Assaf, Peer, Dan
Format Journal Article
LanguageEnglish
Published Weinheim Wiley Subscription Services, Inc 01.04.2022
Subjects
Cancer
cancer‐targeted therapy
Cell death
chemo‐immunotherapy
HO1‐targeted nanotherapeutics
Immunotherapy
ionizable lipid nanoparticle
Lipids
Lymphocytes
Materials science
targeted lipid nanoparticle
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Summary:Immunotherapy In article number 2106350, Dan Peer and co‐workers propose a strategy to boost chemo‐immunotherapy by using a dual cell‐targeted lipid nanotherapeutic boost. With this approach, chemo‐induced immunogenic cancer cell death is increased, tumor myeloid cell is reprogrammed, and cytotoxic T cell is recruited, which consequently improves responsiveness to immunotherapy.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202270099