Anticancer Potency of Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate in Kombucha

Kombucha has an anticancer potency because it has dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate compound. The research aimed to verify the compound dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate as an anticancer with the in-silico method, namely the molecular docking approach, drug like...

Full description

Saved in:
Bibliographic Details
Published inJurnal biodjati (Online) Vol. 7; no. 1; pp. 86 - 94
Main Authors Taupiqurrohman, Opik, Rezaldi, Firman, Amalia, Dina, Suryani, Yani
Format Journal Article
LanguageEnglish
Published UIN Sunan Gunung Djati 30.05.2022
Subjects
dimethyl 2- (2-hydroxy-2-methoxypropilidine) malonate, egfr, in silico, kombucha
Online AccessGet full text

Cover

More Information
Summary:Kombucha has an anticancer potency because it has dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate compound. The research aimed to verify the compound dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate as an anticancer with the in-silico method, namely the molecular docking approach, drug likeness profile, and ADMET test. The tools used were the PyRx, Discovery Studio Visualizer, Sanjeevini, and pkCSM. The research material consisted of 3D Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate and Epidermal Growth Factor Receptor (EGFR). The analysis showed Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate is safe for consumption and can suppress cancer cells. 
ISSN:2541-4208
2541-4208
DOI:10.15575/biodjati.v7i1.14634