An outlook study on the combination of pharmacotherapy and physical rehabilitation for clinically significant acute ischemic stroke patients

• Published in: Cellular, Molecular and Biomedical Reports Vol. 4; no. 3; pp. 168 - 176
• Main Authors: Poluri, Koteswari, Swapna, Bujagouni, Jyothsna, Vatte, Fathima, Kaneez, Afreen, Omamah, Jabeen, Shaheroz, Sultana, Sumera
• Format: Journal Article
• Language: English
• Published: Global Sciences 01.09.2024
• Subjects: anti-platelets; atherosclerosis; pharmacotherapy; rehabilitation; stroke; thrombolytics; thrombus
• ISSN: 2823-2550; 2823-2550
• DOI: 10.55705/cmbr.2023.421498.1185

The occurrence of an ischemic stroke arises from the unfortunate circumstance in which a blood vessel becomes impeded or obstructed, resulting from the presence of a clot, atherosclerosis, or the narrowing of arteries. The neurology department of a 300-bed, multi-specialty tertiary teaching hospital was the site of this six-month observational study. Prescriptions for both inpatients and outpatients in the neurology unit, totalling 90, are considered according to the inclusion criteria. Patient case sheets, questionnaires, interviews, biomedical and radiological reports, and drug regimen charts are the main data sources. Acute ischemic stroke (AIS) patients are more prevalent in the over-60 age group than in the 20–35 age group. The information obtained indicates that male patients have greater effects than female ones. Furthermore, our research indicates that AIS is more common in obese and overweight people. One of the main risk factors for developing AIS is alcohol drinking, tobacco chewing, and smoking, which affect most AIS patients. Treatment options for acute ischemic stroke (AIS) include intravenous thrombolytic therapy (IVT), anti-platelet therapy, anticoagulant therapy, and adjuvant therapies using statins and drugs based on the comorbidities of the patients. This research highlights that individuals with AIS have shown higher progress when physical rehabilitation is combined with intravenous thrombolytic treatment (IVT) for patients with comorbidities. We found that the individuals who continued taking their medicine and therapy after their discharge from the hospital had better motor strength than those who stopped. Our study concludes that the integration of pharmacotherapy with physical rehabilitation yielded significant enhancements in the functional capacity of individuals affected by stroke.