Perspective Treatment Goals for Brain Protection in Case of Acute Ischemia

Ischemic stroke initiates a cascade of biochemical reactions, among which the processes of free radical oxidation occupy a key place. The most important place in management this disease takes reperfusion therapy, the conduct of which is closely related to the problem of neuroprotection. Use of antio...

Full description

Saved in:
Bibliographic Details
Published inInfusion & Chemotherapy no. 2; pp. 9 - 13
Main Authors Dzyak, L. A., Tsurkalenko, O. S., Suk, V. M.
Format Journal Article
LanguageEnglish
Published Civic Union "Communicable Diseases Intensive Care Association" 24.09.2019
Subjects
ischemia of brain, neuroprotection, reperfusion, ischemic cascade, edaravone
Online AccessGet full text

Cover

More Information
Summary:Ischemic stroke initiates a cascade of biochemical reactions, among which the processes of free radical oxidation occupy a key place. The most important place in management this disease takes reperfusion therapy, the conduct of which is closely related to the problem of neuroprotection. Use of antioxidants is a promising direction for the treatment of ischemic stroke. They have antioxidant effects and could prevent free radical processes. Edaravone is a new low molecular weight free radical scavenger, which inhibits the ischemic cascade. The article provides an overview of studies on the effectiveness and safety of edaravone in patients with ischemic stroke.
ISSN:2663-0338
2709-0957
DOI:10.32902/2663-0338-2019-2-9-13