Diagnostic Value of Short and Long Echo Time in 1H-MRS for Patients with Multiple Sclerosis

The quality of the signal received from metabolites in 1 H-magnetic resonance spectroscopy (MRS) directly depends on physical parameters of the impulse sequence used, namely on Time of Echo (TE). We compare MRS (Achieva 3T PRESS 1 H-MRS (TE = 53 and 144 ms, TR = 2000 ms) data acquired in supraventri...

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Bibliographic Details
Published inApplied magnetic resonance Vol. 48; no. 7; pp. 707 - 714
Main Authors Bogdan, A. A., Kataeva, G. V., Khomenko, J. G., Ilves, A. G., Prakhova, L. N.
Format Journal Article
LanguageEnglish
Published Vienna Springer Vienna 01.07.2017
Springer Nature B.V
Subjects
Atoms and Molecules in Strong Fields
Clinical medicine
Data acquisition
Diagnosis
Laser Matter Interaction
Localization
Magnetic resonance spectroscopy
Metabolism
Metabolites
Multiple sclerosis
NMR
Nuclear magnetic resonance
Organic Chemistry
Original Paper
Physical Chemistry
Physical properties
Physics
Physics and Astronomy
Ratios
Signal quality
Solid State Physics
Spectroscopy/Spectrometry
Spectrum analysis
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Summary:The quality of the signal received from metabolites in 1 H-magnetic resonance spectroscopy (MRS) directly depends on physical parameters of the impulse sequence used, namely on Time of Echo (TE). We compare MRS (Achieva 3T PRESS 1 H-MRS (TE = 53 and 144 ms, TR = 2000 ms) data acquired in supraventricular white matter and medial cortex at two various TE (53 and 144 ms) for patients with the multiple sclerosis (25 patients with the confirmed diagnosis of relapsing-remitting multiple sclerosis and 20 patients with the diagnosis of secondary progressive multiple sclerosis) and control group (21 healthy volunteers, comparable on age), to evaluate advantages and disadvantages of these two Echo Time in clinical practice.
ISSN:0937-9347
1613-7507
DOI:10.1007/s00723-017-0900-2