Structure revision and assignment of absolute stereochemistry of a marine C-21 bisfuranoterpene

The C-21 bisfuranoterpene (-)-isotetradehydrofurospongin-1 (6), previously isolated from a Western Australian Spongia sp., has been reisolated from a specimen of Spirastrella papilosa collected during scientific trawling operations in the Great Australian Eight. A 2D NMR analysis of 6 has prompted r...

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Bibliographic Details
Published inJournal of natural products (Washington, D.C.) Vol. 64; no. 5; pp. 638 - 639
Main Authors Capon, RJ, Jenkins, A, Rooney, F, Ghisalberti, EL
Format Journal Article
LanguageEnglish
Published WASHINGTON Amer Chemical Soc 01.05.2001
Subjects
Chemistry, Medicinal
Life Sciences & Biomedicine
Pharmacology & Pharmacy
Plant Sciences
Science & Technology
SPONGE HIPPOSPONGIA SP
TERPENOIDS
FURANOTERPENE
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Summary:The C-21 bisfuranoterpene (-)-isotetradehydrofurospongin-1 (6), previously isolated from a Western Australian Spongia sp., has been reisolated from a specimen of Spirastrella papilosa collected during scientific trawling operations in the Great Australian Eight. A 2D NMR analysis of 6 has prompted reassignment of the published structure 5, while degradation and chiral HPLC analysis have allowed determination of the absolute stereochemistry.
ISSN:0163-3864
1520-6025
DOI:10.1021/np000477o