A 44-year-old Man with a History of Schizoaffective Disorder

Because the patient said that he had been taking all of his prescribed oral medications, it was believed that the intensification of paranoid delusions might be related to a lower dose of haloperidol. [...]on the day of admission, he received haloperidol decanoate, and all other mentioned medication...

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Bibliographic Details
Published inPsychiatric annals Vol. 40; no. 9; pp. 427 - 429
Main Authors Margetić, Branimir, Aukst-Margetić, Branka, Mars̆anić, Vlatka Boric̆ević
Format Journal Article
LanguageEnglish
Published Thorofare SLACK INCORPORATED 01.09.2010
Subjects
Benzodiazepines
Delirium
Drug dosages
Drug withdrawal
Polypharmacy
Psychotropic drugs
Schizophrenia
Croatia
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Summary:Because the patient said that he had been taking all of his prescribed oral medications, it was believed that the intensification of paranoid delusions might be related to a lower dose of haloperidol. [...]on the day of admission, he received haloperidol decanoate, and all other mentioned medications were prescribed without any changes in their doses. [...]it is possible that the patient could tolerate the medications during chronic administration but could not tolerate suddenly increased cholinergic blockade with drugs in doses he previously tolerated. [...]there is a lack of data related to the development of tolerance to medications with anticholinergic properties in clinical settings.
ISSN:0048-5713
1938-2456
DOI:10.3928/00485713-20100902-012