Simultaneous Determination Method of Aniline and Quinoline in Drinking Water by LC/MS/MS

• Published in: Journal of Environmental Conservation Engineering Vol. 47; no. 5; pp. 278 - 285
• Main Authors: FURUKAWA, Koji, KAWAGUCHI, Toshiyuki, KUDO, Kiyonobu, NAKAZAWA, Tomoko, SATO, Ryohei, FUNASAKA, Ryozo, OKUMURA, Akio
• Format: Journal Article
• Language: Japanese; English
• Published: Osaka Society of Environmental Conservation Engineering 20.07.2018; Japan Science and Technology Agency
• Subjects: Aniline; Calibration; Drinking water; LC/MS/MS; Linearity; Liquid chromatography; Mass spectrometry; Mass spectroscopy; Quinoline; Reproducibility; Test procedures; Validation
• ISSN: 0388-9459; 1882-8590
• DOI: 10.5956/jriet.47.278

In this study, an analysis was conducted for the simultaneous determination method of aniline and quinoline in drinking water using liquid chromatography/tandem mass spectrometry.The calibration curves of aniline and quinoline, obtained from the results of the study, demonstrated good linearity in the range of 1.0 to 20 μg/L of aniline standard and in the range of 0.01 to 0.020 μg/L of quinolone standard. The repeatability of repeated measurements of aniline standard solution (0.02 μg/L, n＝5) was observed to be below 0.82％ and the repeatability of repeated measurements of quinoline standard solution (0.02 μg/L, n＝5) was observed to be below 2.7％. In addition, the repeatability (4.8-5.6％), intermediate precision (4.8-12％), and accuracy (98.8-107％) values obtained via recovery tests for aniline and quinoline in drinking water (aniline: 1.0 μg/L, and quinoline: 0.01 μg/L, n＝5, 5days) satisfied the criteria provided in the guidelines for the validation of testing methods for drinking water notified by the Ministry of Health, Labour and Welfare, Japan.