Choice of rational tactics of treatment of bacterial vaginosis

• Published in: Ginekologiâ (Moskva. Online) Vol. 16; no. 4; pp. 11 - 13
• Main Authors: T Yu Pestrikova, E A Yurasova, T D Kovaleva, E V Loseva, L V Sbitneva
• Format: Journal Article
• Language: Russian
• Published: IP Berlin A.V 01.08.2014
• Subjects: amsel criteria; bacterial vaginosis; neo-penotran; the polymerase chain reaction in real time; the preparations of 5-nitroimidazoles
• ISSN: 2079-5696; 2079-5831
• DOI: 10.26442/2079-5831_16.4.11-13

The study involved 49 patients aged 20 to 35 years old, seeking antenatal care with complaints about the presence of vaginal discharge, with a characteristic odor. Verification of the diagnosis of bacterial vaginosis was based on clinical, laboratory examination: Amsel criteria, direct microscopic study, polymerase chain reaction (PCR) in real time. Patients were divided into 2 groups, depending on the results of the clinical course and laboratory data. Group 1 consisted of 25 patients who during the PCR method in real time revealed the presence of moderate vaginal dysbiosis, with a predominance of anaerobic flora. To this group of patients Neo-Penotran® was administered for 7 days. The group 2 included 24 patients who during diagnosis by PCR revealed the presence of vaginal dysbiosis pronounced, with a predominance of mixed dysbiosis. To this group of patients, we administered a combined preparation of Neo-Penotran® Forte (7 days). The results obtained indicate the absence of relapse within 3 months after therapy. Therefore, during diagnosis and the verification of a diagnosis of bacterial vaginosis is necessary to estimate the degree of vaginal dysbacteriosis using, including but routine methods, polymerase chain reaction, real-time. Appointment of treatments for bacterial vaginosis should be commensurate with the violations of the habitat of the vagina.