The Nature and Significance of Pseudo-Dick Reactions
Summary Filtrates of cultures of hemolytic streptococcus contain very little streptococcal protein, and the hypothesis, which considers such protein a frequent source of pseudo-Dick reactions, appears untenable. The activity of filtrate of a non-scarlatinal streptococcus in the skin did not appear t...
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| Published in | The Journal of immunology (1950) Vol. 37; no. 6; pp. 535 - 548 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Am Assoc Immnol
01.12.1939
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| Online Access | Get full text |
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| Summary: | Summary
Filtrates of cultures of hemolytic streptococcus contain very little streptococcal protein, and the hypothesis, which considers such protein a frequent source of pseudo-Dick reactions, appears untenable. The activity of filtrate of a non-scarlatinal streptococcus in the skin did not appear to depend on cellular disintegration, and differed in its great heat-stability and in other respects from that of preparations of streptococcal protein. No agent could be found, other than scarlatinal toxin, which had the potency necessary to induce reactions to 1 or 2 STD of the scarlatinal filtrates used. On the whole, these results tend to suggest that, at least in the age-group studied, pseudo-Dick reactions to serum-free filtrate are unusual, and controls heated for two hours at 100° should be of value in detecting them when they occur. |
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| ISSN: | 0022-1767 1550-6606 |
| DOI: | 10.4049/jimmunol.37.6.535 |