Achieving Biofunctional Micropatterns via Protein‐Based Aqueous Photoresists with Tailored Functionalities (Small 19/2025)

Photolithography Traditional photoresists used in photolithography are typically toxic, nonaqueous substances that require harsh processing conditions, which limits the development of biofunctional and biocompatible micropatterns. In article number 2411900, Xiaorui Zheng, Chengchen Guo, and colleagu...

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Published inSmall (Weinheim an der Bergstrasse, Germany) Vol. 21; no. 19
Main Authors Wang, Jiaqi, Li, Zishun, Wang, Min, Shang, Hongpeng, Ding, Jie, Zheng, Xiaorui, Guo, Chengchen
Format Journal Article
LanguageEnglish
Published Weinheim Wiley Subscription Services, Inc 01.05.2025
Subjects
aqueous photoresist
biofunctional micropattern
chemically modified protein
diagnostics
Micropatterning
Photoresists
Silk fibroin
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ISSN1613-6810
1613-6829
DOI10.1002/smll.202570149

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Summary:Photolithography Traditional photoresists used in photolithography are typically toxic, nonaqueous substances that require harsh processing conditions, which limits the development of biofunctional and biocompatible micropatterns. In article number 2411900, Xiaorui Zheng, Chengchen Guo, and colleagues introduce a protein‐based aqueous photoresist derived from chemically modified silk fibroin. This photoresist employs an entirely water‐based process to achieve high‐resolution multiplexed micropatterning with designed functionalities, demonstrating significant potential in biomedical applications.
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ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202570149