Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study
Aim. To study the incidence and risk factors of cardiovascular events (CVEs) during an 8-year follow-up of a cohort of men aged 25-44 years (Novosibirsk). Material and methods . The cohort study included 1415 people aged 37,33 [31,83; 41,92] years (Median, Me [interquartile range, Q25; Q75], of whic...
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Published in | Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika Vol. 22; no. 1; p. 3393 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English Russian |
Published |
SILICEA-POLIGRAF» LLC
01.02.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Aim.
To study the incidence and risk factors of cardiovascular events (CVEs) during an 8-year follow-up of a cohort of men aged 25-44 years (Novosibirsk).
Material and methods
. The cohort study included 1415 people aged 37,33 [31,83; 41,92] years (Median, Me [interquartile range, Q25; Q75], of which 670 (47,3%) were men. Median follow-up period was 6,9 [5,8; 7,8] years. CVEs were identified using the "Registry of Acute Myocardial Infarction", fatal cases — from the "Medical Certificates of Cause of Death". The examination program included a questionnaire, anthropometry, biochemical studies. Statistical processing was carried out using SPSS (version 13.0).
Results.
Thirteen CVEs were identified, of which 6 were fatal. Survival prognosis was more favorable in men without hypertension, with a heart rate (HR) <80 bpm. The risk of CVEs increased by 14% with an increase in fasting plasma glucose by 0,5 mmol/l, by 1,8 times with creatinine increase by 10 pmol/l (decreased by 29% with an increase in glomerular filtration rate by 5 ml/min /1,73 m
2
); 2 times with a heart rate increase by 10 bpm, regardless of other cardiometabolic risk factors.
Conclusion.
Significant risk factors for fatal and non-fatal CVEs in men aged 25-44 years are hypertension, heart rate >80 bpm, increased fasting plasma glucose, creatinine levels (or decreased glomerular filtration rate). |
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ISSN: | 1728-8800 2619-0125 |
DOI: | 10.15829/1728-8800-2023-3393 |