Analysis of creams. V. Application of thin layer chromatography. Part I

A standard procedure, consisting of two TLC systems, for the qualitative control of creams is presented. All common cream excipients, except those of very high polarity, are separated in a simple gradient elution system, using diethyl ether as the eluent in a chromatographic chamber saturated with n...

Full description

Saved in:
Bibliographic Details
Published inPharmaceutisch weekblad. Scientific edition Vol. 5; no. 3; p. 109
Main Authors Van de Vaart, F J, Hulshoff, A, Indemans, A W
Format Journal Article
LanguageEnglish
Published Netherlands 24.06.1983
Subjects
Chromatography, Thin Layer - methods
Emulsions - analysis
Excipients - analysis
Online AccessGet more information

Cover

More Information
Summary:A standard procedure, consisting of two TLC systems, for the qualitative control of creams is presented. All common cream excipients, except those of very high polarity, are separated in a simple gradient elution system, using diethyl ether as the eluent in a chromatographic chamber saturated with n-pentane. The very polar cream base components are separated using n-butanol-glacial acetic acid-water (20 + 2 + 5) as the eluent. The chromatographic behaviour of common cream excipients as well as three FNA cream bases and four commercial cream bases is discussed.
ISSN:0167-6555
DOI:10.1007/BF01960986