Invaginating Neurofibroma of the Colon

• Published in: Nippon Shokaki Geka Gakkai zasshi Vol. 27; no. 9; pp. 2186 - 2190
• Main Authors: Adachi, Kazuhito, Kudo, Shum, Mori, Hiroyuki, Horiuchi, Yoshimi, Kameyama, Jinichi, Tsukamoto, Masaru
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society of Gastroenterological Surgery 1994
• Subjects: anti-S-100 antibody; invagination; neurofibroma of the colon
• ISSN: 0386-9768; 1348-9372
• DOI: 10.5833/jjgs.27.2186

We report an extremely rare case of invaginating neurofibroma of the colon that was not associated with von Recklinghausen's disease. The patient was an 80-year-old woman whose complaints were melena and intermittent abdominal pain. Barium enema study, endoscopic examination and CT scan showed that an intraluminal tumor of the ascending colon measuring over 5 cm invaginated the transverse colon, and indicated that the tumor was non-epithelial. Right hemi-colectomy was done. The postoperative histological findings showed that the tumor was a neurofibroma. Neurofibroma must be differentiated from other non-epithelial tumors. This histological classification can be achieved by hematoxillin-eosin staining and immunohistochemical study with anti-myoglobin antibody, anti-S-100 antibody and so on. This patient is the fifth such case reported in Japan.