ChemInform Abstract: Synthesis of Novel 1,2,3-Triazole Incorporated Quinoline Derivatives via Click Chemistry and Evaluation of Their Antimalarial Activity

None of the new title compounds (IV) and (VI) show any significant antimalarial activity, but they are found to be non cytotoxic indicating their safety in the mammalian system.

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Bibliographic Details
Published inChemInform Vol. 46; no. 19; p. no
Main Authors Mamgain, Ritu, Atheaya, Himanshu, Khan, Shabana I., Manohar, Sunny, Rawat, Diwan S.
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 01.05.2015
WILEY‐VCH Verlag
Wiley Subscription Services, Inc
Subjects
cycloaddition reactions
medicinal chemistry
pharmacology
pharmacology, medicinal chemistry, vaccines, serums
quinoline derivatives
serums
triazole derivatives
vaccines
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Summary:None of the new title compounds (IV) and (VI) show any significant antimalarial activity, but they are found to be non cytotoxic indicating their safety in the mammalian system.
Bibliography:ark:/67375/WNG-K44KN6K8-G
istex:1885DA42FB0952185CF7E39F83A9F3931CC7F951
ArticleID:CHIN201519199
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201519199