Diabetic Ketoacidosis Associated with Non-occlusive Mesenteric Ischemia in a Subject with Type 2 Diabetes Mellitus: A Case Report

An 81-year-old man was brought to our institution because of general fatigue, loss of appetite, and decreased consciousness. Based on the clinical findings, the patient was diagnosed with diabetic ketoacidosis (DKA) and started on insulin therapy. Two days after normalization of the ketone body leve...

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Published inInternal medicine (Tokyo, 1992)
Main Authors Kimura, Tomohiko, Kubo, Masato, Takahashi, Kaio, Tatsumi, Fuminori, Katakura, Yukino, Shimoda, Masashi, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Format Journal Article
LanguageEnglish
Published Japan 07.08.2025
Subjects
Intestine necrosis
Type 2 diabetes mellitus
Dehydration
Non-occlusive mesenteric ischemia
Diabetic ketoacidosis
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Summary:An 81-year-old man was brought to our institution because of general fatigue, loss of appetite, and decreased consciousness. Based on the clinical findings, the patient was diagnosed with diabetic ketoacidosis (DKA) and started on insulin therapy. Two days after normalization of the ketone body level, he developed a high fever and abdominal pain. Imaging findings revealed a necrotic lesion in the intestine, and surgery was performed. Macroscopic findings showed a necrotic lesion and no thrombi. Finally, the patient was diagnosed with non-occlusive mesenteric ischemia (NOMI). We should be aware of the possibility of NOMI in subjects with DKA, especially those who have abdominal pain even after normalization of ketone body levels.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0918-2918
1349-7235
1349-7235
DOI:10.2169/internalmedicine.5623-25