Robot-assisted partial nephrectomy in 95 consecutive patients: Oncological and functional outcomes at 3 years of follow-up

• Published in: Actas urológicas españolas (English ed.) Vol. 40; no. 4; pp. 217 - 223
• Main Authors: Castillo, O.A, Rodríguez-Carlin, A, Borgna, V
• Format: Journal Article
• Language: English
• Published: Elsevier España 01.05.2016
• Subjects: Carcinoma de células renales; Cirugía conservadora de nefronas; Conservative nephron surgery; Nefrectomía parcial robótica; Oncological results; Renal cell carcinomas; Resultados oncológicos; Robot-assisted partial nephrectomy; Urology; Robot-assisted partial nephrectomy; Oncological results; Cirugía conservadora de nefronas; Resultados oncológicos; Nefrectomía parcial robótica; Conservative nephron surgery; Carcinoma de células renales; Renal cell carcinomas
• ISSN: 2173-5786; 2173-5786
• DOI: 10.1016/j.acuroe.2016.02.014

Abstract Background We present the oncological and functional results from a series of 43 patients with renal tumors, treated consecutively with robot-assisted partial nephrectomy (RPN). Materials and method Between 2010 and 2014, we performed 95 RPNs. To assess the results, we included only those patients ( n = 43) who had a minimum follow-up of 2 years. A descriptive analysis was conducted of the demographic characteristics and perioperative variables. We employed Kaplan–Meier curves to assess overall survival, cancer-specific survival and recurrence-free survival. Results The patients’ mean age was 53.1 ± 13.5 years. The mean preoperative tumor size was 3.7 ± 2.3 cm. The mean surgical time was 102.2 ± 37.1 min. The mean ischemia time was 21.27 ± 7.74 min, with a median intraoperative bleeding volume of 150 ml (IQR, 87.5–425). There was a 7% rate of postoperative complications (Clavien ≥III). There was no mortality. The average Fürhman grade was 2.5 ± 0.56. There were no positive surgical margins or local recurrences. The median follow-up was 38 ± 8 months, with an overall survival, recurrence-free survival and cancer-specific survival of 100% at 3 years of follow-up. The recurrence-free survival was 92,3% at 48 months of follow-up. The mean preoperative glomerular filtration rate was 91.04 ± 28.17 ml/min/1.73 m2 , and the postoperative rate was 89.9 ± 27.69 ml/min/1.73 m2 , with a nonsignificant reduction ( p = 0.74). Conclusions The functional and oncological results of our series confirm the safety and efficacy of RPN. RPN offers optimal preservation of renal function and oncological control in the medium term.