Pediatric Motility Disorders

Purpose of Review Pediatric gastrointestinal motility disorders are a heterogeneous group of enteric nervous system disorders that continue to cause difficulties in children. The pathophysiology, diagnosis, and treatments of the most common disorders of the esophagus, stomach, small intestine, and c...

Full description

Saved in:
Bibliographic Details
Published inCurrent pediatrics reports (Philadelphia, PA) Vol. 5; no. 3; pp. 167 - 175
Main Authors Fiorino, Kristin N., Sood, Manu R.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.09.2017
Subjects
Gastrology (S Khan
Medicine
Medicine & Public Health
Pediatrics
Section Editor
Topical Collection on Gastrology
Achalasia
Chronic intestinal pseudoobstruction syndrome (CIP)
Gastrointestinal dysmotility
Hirschsprung’s disease (HD)
Gastroparesis
Enteric nervous system (ENS)
Online AccessGet full text

Cover

More Information
Summary:Purpose of Review Pediatric gastrointestinal motility disorders are a heterogeneous group of enteric nervous system disorders that continue to cause difficulties in children. The pathophysiology, diagnosis, and treatments of the most common disorders of the esophagus, stomach, small intestine, and colon will be discussed to understand the interplay between motility and sensory functions and the effect on gastrointestinal motility. Recent Findings Much remains unanswered in the pathogenesis of the majority intestinal motility disorders. Research has started to explore targeted gene mutations as potential causes of congenital motility disorders, which may be able to help better predict outcomes. Summary An understanding of the relationship between the enteric nervous system the gastrointestinal tract, in combination with advancements in motility studies, technology, and gene therapies, will help point towards potential for novel therapies.
ISSN:2167-4841
2167-4841
DOI:10.1007/s40124-017-0137-4