ChemInform Abstract: Organocatalytic Asymmetric Vinylogous Michael Addition of Dicyanoolefins to Imine Intermediates Generated in situ from Arenesulfonylalkylindoles

The present first Michael addition provides an easy and convenient approach to C‐3 alkyl‐substituted indole derivatives with high enantioselectivities whereas diastereoselectivity depends on the cyano substrate.

Saved in:
Bibliographic Details
Published inChemInform Vol. 44; no. 15; p. no
Main Authors Zhu, Xing-Li, He, Wu-Jun, Yu, Liang-Liang, Cai, Chang-Wu, Zuo, Zong-Le, Qin, Da-Bin, Liu, Quan-Zhong, Jing, Lin-Hai
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 09.04.2013
WILEY‐VCH Verlag
Wiley Subscription Services, Inc
Subjects
C-C bond formation
diastereoselective syntheses
diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism)
enantioselective syntheses (incl. cis/trans-isomerism)
indole derivatives
indole derivatives, isoindole derivatives
isoindole derivatives
nitriles (benzene compounds)
organocatalysis
pyrazole derivatives
thiopyran derivatives
Online AccessGet full text

Cover

More Information
Summary:The present first Michael addition provides an easy and convenient approach to C‐3 alkyl‐substituted indole derivatives with high enantioselectivities whereas diastereoselectivity depends on the cyano substrate.
Bibliography:ark:/67375/WNG-MX69HT0H-J
istex:0016F45078C878EC2A29E957F3CB156A489E7354
ArticleID:CHIN201315102
ObjectType-Article-1
SourceType-Scholarly Journals-1
content type line 14
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201315102