Analysis of the patients’ life quality with senile asthenia syndrome and chronic kidney disease during renal replacement therapy

• Published in: Izvestii͡a︡ vysshikh uchebnykh zavedeniĭ. Povolzhskiĭ region no. 1
• Main Authors: Petrov, M.V., Belugina, T.N., Burmistrova, L.F.
• Format: Journal Article
• Language: English
• Published: Penza State University Publishing House 01.04.2022
• Subjects: chronic kidney disease; geriatrics; quality of life
• ISSN: 2072-3032
• DOI: 10.21685/2072-3032-2022-1-1

Background. The increase in patients with terminal renal insufficiency is becoming a global trend, in this regard, the question of the quality of life (QOL) of such a category of patients becomes extremely relevant. There is also currently a progressive aging of the population, thereby causing more and more attention to gerontological patients. Materials and methods. 27 patients with stage 5 chronic kidney disease (CKD) and senile asthenia syndrome (SA) were selected, the patients were divided into 2 groups: 1 group received renal replacement therapy (RRT) by hemodialysis, 2 – RRT by peritoneal dialysis, then two control groups were formed: 1 included practically healthy individuals, 2 – patients with CA syndrome without signs of CKD. The comorbid pathology leading to the development of CKD, the most pronounced signs of CA and the assessment of QL were determined. Results. When analyzing comorbid pathology leading to the formation of CKD, the following data were obtained: in group 1, diabetic nephropathy was the most common, in the second group, hypertensive nephroangiosclerosis, probably due to the method of selecting patients for various variants of RRT. In patients with CA in combination with stage 5d CKD, a decrease in labor status and role-playing physical activity is most pronounced, with a minimal decrease in cognitive functions, mental health and the quality of social interaction. Conclusions. The peritoneal dialysis group had the worst indicators of physical status. Cognitive functions and mental status in both groups were comparable, but significantly lower than in those examined with CA without signs of CKD. The data obtained indicate the need to assess the quality of life in patients with stage 5d CKD, since such information should be taken into account both by clinicians to correct patient management tactics and by social workers to help in rational employment.