Conjunctival myeloid sarcoma in acute myeloblastic leukemia-M1

Abstract Clinical case A 69-year-old man with a history of acute myeloblastic leukemia-M1 presented with bilateral conjunctival injection. Ophthalmological examination revealed lesions located at the upper tarsal conjunctiva of the right eye and lower tarsal conjunctiva of both eyes. Histological an...

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Published inArchivos de la Sociedad Española de Oftalmología (English ed.) Vol. 87; no. 3; pp. 79 - 81
Main Authors Méndez-Cepeda, P, Millán-Rodríguez, A.C, Dios, E, Alvarez, C, Sevillano, C
Format Journal Article
LanguageEnglish
Published Elsevier España 01.03.2012
Subjects
Acute myeloblastic leukemia
Conjunctiva
Conjuntiva
Immunohistochemistry
Inmunohistoquímica
Leucemia mieloblástica aguda
Myeloid sarcoma
Ophthalmology
Prognosis
Pronóstico
Sarcoma granulocítico
Immunohistochemistry
Myeloid sarcoma
Prognosis
Inmunohistoquímica
Pronóstico
Leucemia mieloblástica aguda
Conjuntiva
Sarcoma granulocítico
Acute myeloblastic leukemia
Conjunctiva
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Summary:Abstract Clinical case A 69-year-old man with a history of acute myeloblastic leukemia-M1 presented with bilateral conjunctival injection. Ophthalmological examination revealed lesions located at the upper tarsal conjunctiva of the right eye and lower tarsal conjunctiva of both eyes. Histological and immunohistochemical studies confirmed conjunctival myeloid sarcoma (MS). The patient died due to multiorgan failure three months later. Discussion Extramedullary recurrence of leukemia can appear as an ocular manifestation that brings about a recurrence of the leukemia, leading to a poor prognosis.
ISSN:2173-5794
2173-5794
DOI:10.1016/j.oftale.2012.05.011