Primary Hepatic Amyloidosis Presenting as Nodular Masses on the Background of Diuse Inltration and Extreme Liver Stiness on MR Elastography

Amyloidosis is characterized by the deposition of extracellular protein material, amyloid, in various organs.The clinical and imaging features of the disease are often nonspecific and a tissue biopsy is often required. We present the case of a 64-year-old man with biopsy proven amyloidosis of the li...

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Published inJournal of gastrointestinal and liver diseases : JGLD Vol. 23; no. 4; pp. 437 - 440
Main Authors Srinivasan, Sivasubramanian, Tan, Yi Qi, Teh, Hui Seong, Lee, Piao Jarrod, Khoo, Ree Nee
Format Journal Article
LanguageEnglish
Published 01.12.2014
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Summary:Amyloidosis is characterized by the deposition of extracellular protein material, amyloid, in various organs.The clinical and imaging features of the disease are often nonspecific and a tissue biopsy is often required. We present the case of a 64-year-old man with biopsy proven amyloidosis of the liver. The patient presented with non-specific clinical symptoms. Routine imaging showed hepatomegaly with heterogeneous enhancement, and several large nodular space occupying lesions, mimicking neoplasm. MR elastography revealed an extremely stiff liver. Amyloidosis presenting as multiple nodular masses on the background of diffuse infiltrative pattern or demonstration of extreme stiffness in hepatic amyloidosis on MR elastography have not been described previously.
ISSN:1841-8724
1842-1121
DOI:10.15403/jgld.2014.1121.234.hamy