RETRACTED ARTICLE : Comparison of supraglottic airway device vs. endotracheal intubation for initial airway management in out-of-hospital cardiac arrest: a systematic review and meta-analysis

• Published in: Expert review of medical devices Vol. 22; no. 7; p. i
• Main Authors: Tao, Yan, Zhang, Juxia, Feng, Lei
• Format: Journal Article
• Language: English
• Published: England 03.07.2025
• Subjects: Airway Management - instrumentation; Airway Management - methods; Cardiopulmonary Resuscitation; Humans; Intubation, Intratracheal - instrumentation; Out-of-Hospital Cardiac Arrest - mortality; Out-of-Hospital Cardiac Arrest - therapy; sudden death; return of spontaneous circulation; airway management; Cardiac arrest; survival
• ISSN: 1745-2422
• DOI: 10.1080/17434440.2024.2446384

Out-of-hospital cardiac arrest (OHCA) is characterized by the cessation of mechanical cardiac activity and voluntary circulation occurring outside of a hospital setting, making it the leading cause of death worldwide. Recently, the optimal approach to airway management has been a subject of controversy. Follow PRISMA guidelines for systematic evaluation and meta-analysis. The primary outcome was survival assessed by four measures: Restoration of spontaneous circulation, survival to hospital or emergency department, evaluation of functional recovery after PCR (measured at both discharge and 3 months after PCR), and neurological function score at discharge. A total of six RCTs (14,205 patients) were included in the systematic review, and four RCTs (13,053 patients) were included in the meta-analysis. Five studies (83.3%) of RCTs with ETI controls were notable for their high quality, with low risk of bias judged in all 7 domains of the risk assessment scale. Showed an advantage of SGA (compared to ETI) with potential for ROSC (95% CI [1.02 to 1.18], I  = 48%,  = 0.01) and survival to hospital or emergency department (95% CI [1.01 to 1.17], I  = 12%,  = 0.02). This systematic review and meta-analysis found a significant association between SGA and the possibility of obtaining ROSC and reaching the hospital or emergency department after CPR in OHCA.