Assessment of Myocardial Deformation: Predicting Medium-term left Ventricular Dysfunction after Surgery in Patients With chronic Mitral regurgitation
The development of left ventricular dysfunction after mitral valve replacement is a common problem in patients with chronic severe mitral regurgitation. Assessment of myocardial deformation enables myocardial contractility to be accurately estimated. Our aim was to compare the value of the preoperat...
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Published in | Revista española de cardiología (English ed.) Vol. 63; no. 5; pp. 544 - 553 |
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Main Authors | , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier Espana
01.05.2010
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Subjects | |
Online Access | Get full text |
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Summary: | The development of left ventricular dysfunction after mitral valve replacement is a common problem in patients with chronic severe mitral regurgitation. Assessment of myocardial deformation enables myocardial contractility to be accurately estimated. Our aim was to compare the value of the preoperative strain and strain rate derived by either speckle-tracking echocardiography or tissue Doppler imaging (TDI) for predicting the medium-term decrease in left ventricular ejection fraction (LVEF) following surgery.
This prospective study involved 38 consecutive patients with chronic severe mitral regurgitation who were scheduled for mitral valve replacement. The longitudinal strain and strain rate in the interventricular septum were measured preoperatively using speckle-tracking echocardiography and TDI. The LVEF was determined preoperatively and postoperatively using 3-dimensional echocardiography. Echocardiographic assessments were performed in the 48 hours prior to surgery and 6 months postoperatively.
The patients’ mean age was 59.9±11.3 years and 10 (29.4%) were male. Both speckle-tracking echocardiography and TDI were found to be predictors of a >10% decrease in LVEF at 6 months. However, the predictive value of speckle-tracking echocardiography was greater than that of TDI. The longitudinal strain at baseline in the interventricular septum as measured by speckle-tracking echocardiography was the most powerful predictor; the area under the curve was 0.85 and the optimal cut-off value was –0.11.
Speckle-tracking echocardiography can be used to predict a decrease in LVEF over the medium term after mitral valve replacement. Moreover, the predictive accuracy of speckle-tracking echocardiography was greater than that of TDI.
El desarrollo de disfunción ventricular izquierda tras la sustitución valvular mitral es un problema frecuente en pacientes con insuficiencia mitral grave crónica. El análisis de la deformación miocárdica permite estimar con precisión la contractilidad miocárdica. Nuestro objetivo fue comparar el valor predictivo de
strain (S) y
strain rate (SR) preoperatorios obtenidos por
speckle-tracking y Doppler tisular (DTI) para predecir la disminución de la fracción de eyección del ventrículo izquierdo (FEVI) a medio plazo tras la cirugía.
Treinta y ocho pacientes consecutivos con insuficiencia mitral grave crónica programados para sustitución valvular mitral fueron incluidos prospectivamente. Se analizó el S y el SR longitudinal del septo interventricular en el periodo preoperatorio mediante
speckle-tracking y DTI. La FEVI preoperatoria y postoperatoria se obtuvo por ecocardiografía tridimensional. Los estudios ecocardiográficos se realizaron dentro de las 48 h previas a la cirugía y 6 meses después de la cirugía.
La media de edad de los pacientes era 59,9 ± 11,3 años; 10 pacientes (29,4%) eran varones. Tanto el
speckle-tracking como el DTI resultaron predictores de disminución de la FEVI > 10% a 6 meses. Sin embargo, el valor predictivo del
speckle-tracking fue superior al del DTI. El S longitudinal del septo interventricular basal mediante
speckle-tracking fue el parámetro con mayor poder predictivo, con un área bajo la curva de 0,85 y un punto de corte óptimo de -0,11.
El
speckle-tracking permite predecir la disminución de la FEVI a medio plazo tras la sustitución valvular mitral. Además, el
speckle-tracking es más preciso que el DTI para este fin. |
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ISSN: | 1885-5857 1885-5857 |
DOI: | 10.1016/S1885-5857(10)70116-X |