Palladium catalyzed alkenylation or alkynylation at C-5 of uracil nucleosides using novel phenylidonium triflate

A new coupling reaction between novel uracil-5-iodonium triflate and unsaturated stannane or alkenyl boronic acid is described. The reaction is achieved via palladium catalyzed cross-coupling reaction under mild conditions within short reaction time. Alkenyl or alkynyl moieties were readily introduc...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 40; no. 10; pp. 1903 - 1906
Main Authors Roh, Kyoung Rok, Kim, Joong Young, Kim, Yong Hae
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.03.1999
Online AccessGet full text

Cover

More Information
Summary:A new coupling reaction between novel uracil-5-iodonium triflate and unsaturated stannane or alkenyl boronic acid is described. The reaction is achieved via palladium catalyzed cross-coupling reaction under mild conditions within short reaction time. Alkenyl or alkynyl moieties were readily introduced by palladium catalyzed coupling of 5-phenyliodonium trifllate substituted uracil nucleosides with organostannane or organoboron compounds under mild conditions in good yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(98)02491-5