Determination of Specific Absorbance (A¦) for Six Psychoactive Drugs Encountered in Forensic Toxicology
Abstract Specific absorbance (A¦) is defined as the maximum absorbance of a 1% solution over a 1-cm path length measured via spectroscopy. Finding a reliable value for specific absorbance for a drug provides an important tool for the quantitative verification of concentration of analytical standards...
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| Published in | Journal of analytical toxicology Vol. 44; no. 6; pp. 531 - 540 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
31.07.2020
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| Online Access | Get full text |
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| Summary: | Abstract
Specific absorbance (A¦) is defined as the maximum absorbance of a 1% solution over a 1-cm path length measured via spectroscopy. Finding a reliable value for specific absorbance for a drug provides an important tool for the quantitative verification of concentration of analytical standards. Although many new drugs have emerged within the last ten years, many either do not have a reliable value for A¦, or a value simply has never been published. This work focused on determining the quantitative value of the specific absorbance of six psychoactive drugs using ultraviolet-visible spectroscopy, as well as comparing A¦ values of drugs purchased in 2017 to A¦ of their counterparts purchased in 2019. The drugs analyzed included Iloperidone, Risperidone, Aripiprazole, Vilazodone, Vortioxetine and Suvorexant. |
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| ISSN: | 0146-4760 1945-2403 |
| DOI: | 10.1093/jat/bkz091 |