Epstein-Barr virus latent membrane protein-1 expression in Hodgkin lymphoma
Expression of latent membrane protein-1 of Epstein-Barr virus is documented in Hodgkin lymphoma indicating its relationship in disease process. A total of 50 cases of Hodgkin lymphoma were analyzed for latent membrane protein-1 expression by immunohistochemistry. The mean age was 28.7 years with mal...
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Published in | Bangabandhu Sheikh Mujib Medical University journal Vol. 11; no. 3; pp. 203 - 208 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Bangabandhu Sheikh Mujib Medical University
01.09.2018
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Online Access | Get full text |
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Summary: | Expression of latent membrane protein-1 of Epstein-Barr virus is documented in Hodgkin lymphoma indicating its relationship in disease process. A total of 50 cases of Hodgkin lymphoma were analyzed for latent membrane protein-1 expression by immunohistochemistry. The mean age was 28.7 years with male predominance. Mixed cellularity classical Hodgkin lymphoma was the commonest subtype (50% cases). Out of 50 cases, 48% cases were found positive for latent membrane protein. Of the five histologic subtypes, all cases of lymphocyte depleted classical Hodgkin lymphoma showed positivity which was followed by 60% positivity of mixed cellularity classical Hodgkin lymphoma. Association of latent membrane protein-1 expression in relation to different age group, site of involvement and subtypes of Hodgkin lymphoma were found statistically insignificant while latent membrane protein-1 expression was significantly higher in male than female. |
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ISSN: | 2074-2908 2224-7750 |
DOI: | 10.3329/bsmmuj.v11i3.36813 |