Low testosterone levels are inversely correlated with carotid artery plaque formation in elderly women

To study the relationship between serum testosterone levels and the plaque formation of the carotid artery in a population-based cohort of independently living healthy women above 60 years of age. Analysis of the healthy elders from a population-based cohort study in 9 communities of Beijing. Caroti...

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Bibliographic Details
Published inZhongguo ying yong sheng li xue za zhi Vol. 29; no. 6; p. 554
Main Authors Ma, Qiang, Cheng, Qing-Li, Ma, Jian, Ao, Qiang-Guo, Tan, Guo-Juan, Zhi, Guang
Format Journal Article
LanguageChinese
Published China 01.11.2013
Subjects
Aged
Atherosclerosis - blood
Carotid Arteries - pathology
Carotid Intima-Media Thickness
Carotid Stenosis - blood
Female
Humans
Male
Prospective Studies
Testosterone - blood
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Summary:To study the relationship between serum testosterone levels and the plaque formation of the carotid artery in a population-based cohort of independently living healthy women above 60 years of age. Analysis of the healthy elders from a population-based cohort study in 9 communities of Beijing. Carotid intima-media thickness and atherosclerotic plaques were determined ultrasonographically. Serum testosterone levels were measured by immunoassay. The data were analyzed with ANOVA and logistic regression analysis. There was an inverse correlation between testosterone and plaque formation in old females (P < 0.01), while no association was found in males. Female with testosterone levels in the lowest quartile (< 0.49 nmol/L) had more risk of plaque formation (OR = 3.805, P < 0.01) after adjusted with age and other traditional factors of atherosclerosis. Testosterone concentrations are negatively associated with carotid artery atherosclerosis in old women in Beijing, experimental and prospective studies are needed t
ISSN:1000-6834