Search for Effective Antimycotic Agents against Microsporum Gypseum from 61 Ethno Medicinal Plants of Hyderabad, Karnataka Region, Karnataka, India

The 61 ethno medicinal plants of Hyderabad Karnataka region belonging to 33 different families used in skin diseases were screened for their antidermatophytic properties. Screening was carried out at 5 and 2.5 mg/ml concentrations of pet ether, chloroform, ethyalacetate, methanol and aqueous extract...

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Published inJournal of bioanalysis & biomedicine Vol. 6; no. 2; p. 33
Main Author Shivakumar Singh P, Vidyasagar GM
Format Journal Article
LanguageEnglish
Published OMICS Publishing Group 01.01.2014
Subjects
Achyranthes aspera
Allium
Celosia argentea
Citrus medica
Coccinia
Corchorus
Curcuma longa
Emblica officinalis
Euphorbia tirucalli
Lantana camara
Lawsonia
Life Sciences
Lycopersicon esculentum
Mentha
Microsporum gypseum
Ricinus communis
Tinospora
Tridax procumbens
Zingiber officinale
Microsporum gypseum
Traditional medicinal plants
Traditional medicinal plants Microsporum gypseum Antifungal screening
Antifungal screening
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Summary:The 61 ethno medicinal plants of Hyderabad Karnataka region belonging to 33 different families used in skin diseases were screened for their antidermatophytic properties. Screening was carried out at 5 and 2.5 mg/ml concentrations of pet ether, chloroform, ethyalacetate, methanol and aqueous extracts of each plant by agar well diffusion technique against Microsporum gypseum. Out of 61 plants, 05 (Ceasalpinia bonducella, Coccinia indica, Corchorus oleterius, Lawsonia inermis and Tridax procumbens) showed very effective antidermatophytic activity in ethyl acetate, chloroform and in aqueous extracts, effective activity observed in 11 plants (Achyranthes aspera, Allium sativam, Celosia argentea, Citrus medica, Curcuma longa, Emblica officinalis, Gymnosporia montana, Lycopersicon esculentum, Milletia pinnata, Ricinus communis, Zingiber officinale) in different extracts, whereas 38 plants showed moderate activity, 07 plants (Euphorbia tirucalli, Lantana camara, Mentha viridis, Tinospora cordifolia and Tridax procumbens) showed weak activity. The minimum inhibitory concentrations of 05 very effective plants were determined. The potential minimum inhibitory concentrations of 0.15 mg/ml conc. were detected from C. indica. This study provides scientific base for the isolation and purification of antidermatophytic compound(s) from ethno medicinal plants.
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ISSN:1948-593X
1948-593X
DOI:10.4172/1948-593X.1000106