Transorbital Approach Clipping of Middle Cerebral Artery Aneurysm: A Virtual Reality Morphometric Anatomic Study

• Published in: World neurosurgery
• Main Authors: Piper, Keaton, Saez-Alegre, Miguel, Perillo, Thomas, Peto, Ivo, Najera, Edinson, Williams, Josef, Breton, Jeff, Felbaum, Daniel R., Jean, Walter C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 03.09.2024
• Subjects: Aneurysm clipping; MCA aneurysm; Transorbital approach; Virtual reality; Transorbital approach; TOA; MCA; IQR; MCA aneurysm; CT; SF; Virtual reality; AOF; TL; Aneurysm clipping; LTOA; DOF; VR
• ISSN: 1878-8750; 1878-8769; 1878-8769
• DOI: 10.1016/j.wneu.2024.08.152

The transorbital approach (TOA) has a unique advantage to the more common lateral approaches as it provides direct access to the anterior middle fossa and medial sylvian fissure (SF) without significant dissection or retraction. However, when to use the TOA for surgical treatment of middle cerebral artery (MCA) aneurysms remains unclear. This study details the feasibility of clipping unruptured MCA aneurysms via the TOA by highlighting the anatomic features that either facilitate or hinder the approach. Virtual reality (VR) models of 25 MCA aneurysms from computed tomography angiograms of actual patients were rendered with the relevant anatomic structures, including the neighboring temporal lobe and SF. TOA was performed on the models in VR and the globe was translated medially and inferiorly, replicating retraction used intraoperatively. Anatomic data, including the area of surgical freedom (AOF) at the aneurysm, were recorded. Trials of aneurysm clipping were conducted in VR and each aneurysm was classified as “possible” or “impossible” candidates for clipping via TOA. Separately, the relationship between surgical view and SF visualized was analyzed. Sixteen aneurysms were eliminated as candidates for TOA treatment either through VR clip trial and/or because the SF was inaccessible. The remaining 9 (36%) were candidates for TOA. Comparing the details of these 2 aneurysm categories with Mann Whitney U tests, there was a statistically significant difference in the AOF of the TOA approach and the width of the aneurysm dome. A clinical case report is also provided highlighting the VR rehearsal similarity with surgery. Given the minimally invasive, technically challenging approach, the feasibility and safety of TOA for MCA aneurysms must be evaluated before wide clinical adoption. This study identified AOF, aneurysm width, and SF accessibility as three features that may significantly impact the possibility of clipping MCA aneurysms via TOA.