Lumbar Endoscopic Unilateral Laminectomy for Bilateral Decompression in Degenerative Spondylolisthesis

• Published in: World neurosurgery
• Main Authors: Mitha, Rida, Mahan, Mark A., Patel, Rujvee P., Colan, Jhair Alejandro, Leyendecker, Jannik, Zaki, Mark M., Harake, Edward Samir, Kathawate, Varun, Kashlan, Osama, Konakondla, Sanjay, Huang, Meng, Elsayed, Galal A., Hafez, Daniel M., Pennicooke, Brenton, Agarwal, Nitin, Hofstetter, Christoff P., Ogunlade, John
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 10.09.2024
• Subjects: Degenerative spondylolisthesis; Endoscopy; Laminectomy; LE-ULBD; Degenerative spondylolisthesis; ODI; PROM; VAS; Laminectomy; Endoscopy; FESS; Degenerative Spondylolisthesis
• ISSN: 1878-8750; 1878-8769; 1878-8769
• DOI: 10.1016/j.wneu.2024.09.017

Degenerative spondylolisthesis is an important cause of chronic low back pain and radiculopathy in the adult U.S. population. Open decompression with or without fusion is considered the standard for management, yet optimal treatment remains controversial. Full endoscopic spine surgery offers an alternative surgical approach with possible advantages. There is a paucity of data on the use of full endoscopic spinal surgery in degenerative spondylolisthesis. Therefore, we present the clinical and radiographic outcomes of 73 patients with low-grade degenerative spondylolisthesis with severe stenosis, who underwent lumbar endoscopic unilateral laminectomy for bilateral decompression. Patients with low-grade degenerative spondylolisthesis who underwent a lumbar endoscopic ULBD at 6 spine centers in North America were included in this study. Patients were followed up at 3, 9, and 12 months. Static and dynamic imaging was performed and evaluated routinely before surgery to identify the pathology and grade of spondylolisthesis. Patient-reported outcomes were prospectively collected. This study included 73 patients from 6 spine centers. Sixty-two patients were diagnosed with grade I spondylolisthesis, whereas 11 were diagnosed with grade II spondylolisthesis. Postoperatively, 70 patients reported improved symptoms and pain resolution, whereas 3 patients reported worse pain. Mean visual analog scale back and visual analog scale leg scores and Oswestry Disability Index showed a statistically significant improvement at 3, 9, and 12 months compared with the preoperative period. Radiographically, no patient in our study had progression of the grade of spondylolisthesis. Patients with low-grade degenerative spondylolisthesis causing severe stenosis can safely be treated with lumbar endoscopic unilateral laminectomy for bilateral decompression. A head-to-head trial should be undertaken to provide a higher level of clinical evidence.