Synthesis of new β2,2-amino acids with carbohydrate side chains: impact on the synthesis of peptides
•Synthesis of new geminally disubstituted C-linked carbo-β2,2-amino acids (β2,2-Caas).•Synthesis of new class of peptides.•Impact of carbohydrate side chains on the synthesis of peptides.•The impact on the absence of C-3 –OMe on the β2,2-peptides. The study describes the synthesis of new geminally d...
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Published in | Carbohydrate research Vol. 388; pp. 8 - 18 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier Ltd
31.03.2014
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Subjects | |
Online Access | Get full text |
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Summary: | •Synthesis of new geminally disubstituted C-linked carbo-β2,2-amino acids (β2,2-Caas).•Synthesis of new class of peptides.•Impact of carbohydrate side chains on the synthesis of peptides.•The impact on the absence of C-3 –OMe on the β2,2-peptides.
The study describes the synthesis of new geminally disubstituted C-linked carbo-β2,2-amino acids (β2,2-Caas) with different carbohydrate side chains, and their use in the synthesis of β2,2-peptides. The study infers that the side chain has an influence on the synthesis of peptides and their conformational behaviour. |
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ISSN: | 0008-6215 1873-426X |
DOI: | 10.1016/j.carres.2014.01.026 |