A proton 2D-NMR study of an oligodeoxyribonucleotide containing N6-methyladenine:d(GGm6ATATCC)

The presence of a m6A-T base pair does not give rise to a major change in helix conformation from that of a normal B DNA, but does slow down dramatically the rate of helix formation.

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Bibliographic Details
Published inBiochimie Vol. 67; no. 7-8; pp. 819 - 822
Main Authors Fazakerley, G V, Guy, A, Téoule, R, Quignard, E, Guschlbauer, W
Format Journal Article
LanguageEnglish
Published France 01.07.1985
Subjects
Adenine - analogs & derivatives
Magnetic Resonance Spectroscopy - methods
Nucleic Acid Conformation
Oligonucleotides
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Summary:The presence of a m6A-T base pair does not give rise to a major change in helix conformation from that of a normal B DNA, but does slow down dramatically the rate of helix formation.
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ISSN:0300-9084
DOI:10.1016/S0300-9084(85)80173-5