Haemoglobin F melbourne Gγ16 Gly å Arg and haemoglobin F carlton [formula omitted]. Further evidence for varied activity of γ-chain genes
Two new foetal haemoglobin variants are reported: haemoglobin F Melbourne G γ16 Gly a ̊ Arg forming 29% of the total haemoglobin F in cord blood and haemoglobin F Carlton G γ121 Glu a ̊ Lys forming 26% of the haemoglobin F in cord blood. The amino acid substitution at residue 121 in haemoglobin F Ca...
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Published in | Biochimica et biophysica acta. Protein structure Vol. 490; no. 2; pp. 452 - 455 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Elsevier B.V
01.02.1977
|
Online Access | Get full text |
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Summary: | Two new foetal haemoglobin variants are reported: haemoglobin F Melbourne
G
γ16
Gly
a
̊
Arg
forming 29% of the total haemoglobin F in cord blood and haemoglobin F Carlton
G
γ121
Glu
a
̊
Lys
forming 26% of the haemoglobin F in cord blood. The amino acid substitution at residue 121 in haemoglobin F Carlton is identical to that of haemoglobin F Hull, however, the latter originates from the
A
γ gene while haemoglobin F Carlton arises from the
G
γ gene. |
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ISSN: | 0005-2795 1879-2952 |
DOI: | 10.1016/0005-2795(77)90020-4 |