Should we pay more attention to low creatinine levels?

A review is made of the basic aspects of creatine/creatinine metabolism and the close relationship between creatinine and muscle mass, which makes the former a biochemical marker of the latter. Emphasis is placed on the current prognostic value of both the low urinary excretion of creatinine and low...

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Published inEndocrinología, diabetes y nutrición. Vol. 67; no. 7; pp. 486 - 492
Main Authors Amado Diago, Carlos A., Amado Señaris, José A.
Format Journal Article
LanguageEnglish
Published Elsevier España, S.L.U 01.08.2020
Subjects
Creatinina baja
Low creatinine
Masa muscular
Morbidity
Morbilidad
Mortalidad
Mortality
Muscle mass
Prognosis
Pronóstico
Sarcopenia
Sarcopenia
Creatinina baja
Prognosis
Pronóstico
Mortality
Morbilidad
Mortalidad
Masa muscular
Low creatinine
Muscle mass
Morbidity
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Summary:A review is made of the basic aspects of creatine/creatinine metabolism and the close relationship between creatinine and muscle mass, which makes the former a biochemical marker of the latter. Emphasis is placed on the current prognostic value of both the low urinary excretion of creatinine and low serum creatinine levels in different clinical settings in which sarcopenia probably plays a significant role in morbidity and mortality. Se revisan los aspectos básicos del metabolismo de la creatina/creatinina y la íntima relación entre la creatinina y la masa muscular, lo que la convierte en un marcador bioquímico de ésta. Se hace énfasis en la utilidad pronóstica actual, tanto de la baja excreción urinaria de creatinina como de los niveles bajos de creatinina sérica, en diferentes contextos clínicos en los que la sarcopenia probablemente desempeña un papel importante en la morbilidad y mortalidad.
ISSN:2530-0180
2530-0180
DOI:10.1016/j.endien.2020.09.003