Inhalation beta-2-agonists in cardiorespiratory pathology: pro-or anti-inflammatory effects?

Currently, the increase in comorbid pathology, including patients with bronchoobstructive and cardiovascular diseases remains an urgent problem. Therefore, there is a need not only for new approaches in the tactics of management and treatment of patients with combined cardiorespiratory pathology, bu...

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Bibliographic Details
Published inKliničeskaâ praktika Vol. 9; no. 4; pp. 65 - 73
Main Authors Nistor, S. Yu, Smolyakova, E. V., Klimova, A. A., Rvacheva, A. V., Zykov, K. A.
Format Journal Article
LanguageEnglish
Published Eco-vector 15.12.2018
Subjects
beta2-agonists
cardiorespiratory pathology
cardiovascular diseases
obstructive pulmonary diseases
pro- and anti-inflammatory mechanisms
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Summary:Currently, the increase in comorbid pathology, including patients with bronchoobstructive and cardiovascular diseases remains an urgent problem. Therefore, there is a need not only for new approaches in the tactics of management and treatment of patients with combined cardiorespiratory pathology, but also a more complete understanding of the impact of existing bronchodilator therapy on comorbid pathology and the pathophysiological changes taking place in order to create a new approach to the diagnosis and selection of effective and optimal treatment. The article provides a review of the literature on the impact of beta-2-agonists on pro- and anti-inflammatory mechanisms in patients with bronchial obstruction, including cardiovascular disease.
ISSN:2220-3095
2618-8627
DOI:10.17816/clinpract9465-73