RuII and RuIII complexes with imidazole ligands containing (benzyloxy)pyridinone moiety

[Display omitted] Preparation of novel imidazole ligands containing 3-(benzyloxy)pyridinone moiety is described. The Ruiii and Ruii leader-compounds containing the above-mentioned ligands were synthesized by coordination of imidazole group. The stability of the obtained compounds was explored in buf...

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Published inMendeleev communications Vol. 32; no. 2; pp. 186 - 188
Main Authors Fateeva, Anna A., Shutkov, Ilya A., Mazur, Dmitrii M., Kovaleva, Olga N., Milaeva, Elena R., Nazarov, Alexey A.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.03.2022
Subjects
antiproliferative activity
imidazoles
pyridinone
ruthenium compounds
stability
ruthenium compounds
pyridinone
imidazoles
stability
antiproliferative activity
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Summary:[Display omitted] Preparation of novel imidazole ligands containing 3-(benzyloxy)pyridinone moiety is described. The Ruiii and Ruii leader-compounds containing the above-mentioned ligands were synthesized by coordination of imidazole group. The stability of the obtained compounds was explored in buffer solution and in the presence of DMSO, respectively, and their antiproliferative activity was assessed.
ISSN:0959-9436
DOI:10.1016/j.mencom.2022.03.011