Deconvolution method to split up X-ray peaks emitted by 223Ra

• Published in: Brazilian Journal of Radiation Sciences Vol. 6; no. 1
• Main Authors: Simões, Rafael Figueiredo Pohlmann, Da Silva, Carlos José, Da Silva, Ronaldo Lins, Poledna, Roberto, Da Cruz, Paulo Alberto Lima, De Sá, Lídia Vasconcellos
• Format: Journal Article
• Language: English
• Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 28.01.2018
• Subjects: 223Ra; Area Under Curve; Spectrometry; X-Ray; X-Ray Emission
• ISSN: 2319-0612; 2319-0612
• DOI: 10.15392/bjrs.v6i1.353

The Radium-223 (223Ra) has being used as a medicine for localized treatment of patients with osteoblastic metastasis originated by prostate cancer resistant of castration or hormone refractory. For a better treatment with this radionuclide, clinical images are one path to turn achievable organ's dosimetry for each patient. The X-rays emitted by 223Ra demonstrated as the main way to turn the image acquiring feasible. In order to study this X-ray area, deconvolution is necessary to split up the mains X-ray peaks that are measured by a high-purity germanium detector as doublet peaks in a complex region of the spectrum below 100 keV. For this, the Colegram® code was applied using the Low Energy X Voigt fitting curve on raw data source from Maestro® software. Results of activity using the deconvolution data from this work were in agreement with values obtained at absolute standardization live-time anticoincidence counting. The Colegram® code demonstrates a powerful tool to aid Maestro to split up the mains overlapped X-rays emitted by 223Ra.