0938 A SYSTEMATIC REVIEW OF ADHERENCE TO LONG-TERM NON-INVASIVE VENTILATION IN CHILDREN

• Published in: Sleep (New York, N.Y.) Vol. 40; no. suppl_1; pp. A348 - A349
• Main Authors: Alkhaledi, B, Castro Codesal, ML, Olmstead, D, Featherstone, R, Sebastianski, M, MacLean, JE
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 28.04.2017
• Subjects: Oxygen therapy; Systematic review; Ventilation
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleepj/zsx050.937

Abstract Introduction: Adherence to non-invasive ventilation (NIV) has been shown to optimize both day and nighttime gas exchange in children with documented physiological advantages. Minimal hours of treatment required for optimal effect have not been established. Variability in adherence to NIV in children also requires further examination. In this systematic review we summarized the available data on adherence and factors that influence adherence in children using NIV Methods: This extension of a scoping review on long-term NIV therapies in children identified all publications examining NIV adherence in children; 289 included publications were reviewed to identify those reporting on adherence. Grey literature sources and articles reporting only adherence rates were excluded. Data extraction on study design, sample size, intervention type, adherence measurements, barriers to adherence, and determinants of adherence will be completed Results: Seventy five manuscripts mentioning adherence were identified from the scoping review of which 27 studies (1138 subjects) were included for data extraction. Objective measures of adherence were available in 21 (78%) of the studies. Preliminary analysis showed both patient and technology influences contributing to the variable rates of children’s adherence (e.g. patient age, interface type). Six studies reported on adherence measures, most commonly (70%) defined as an average of 4 or more hours of NIV use per night at least 5 nights a week. Only one study related adherence to outcome. This study reported longer duration of CPAP use correlated inversely with Epworth Sleepiness Scale scores Conclusion: This systematic review revealed gaps in the evidence on objective measures used to assess adherence in long term NIV use in children. The relationship between these measures and clinical outcomes in children was also limited. Identification of factors influencing NIV use in children requires further study in order to understand how to better support children to use long term NIV Support (If Any): None