Analysis of the essential oil from Lantana camara leaves and its cytotoxic potential against T-47D breast cancer cells

Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-M...

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Published inJurnal riset kimia Vol. 12; no. 1; pp. 1 - 9
Main Authors Suryati, Suryati, Aziz, Enda Desriansyah, Efdi, Mai, Wahyuni, Fatma Sri, Hefni, Dira
Format Journal Article
LanguageEnglish
Published Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas 03.04.2021
Subjects
bslt assay
cytotoxic
lantana camara
mtt assay
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Summary:Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-MS analysis show isocaryophyllene (14.39%), ρ-cymene (8.17 %), β-cubebene (7.8 %), α-pinene (7.64 %), and β-elemene (5.51 %) as the main compound. The cytotoxic activity of the isolated essential oil was highly toxic both to Artemia salina shrimp larvae (LC50 15.92 µg/mL) and to breast cancer cells T-47D (IC50 10.67 µM).
ISSN:1978-628X
2476-8960
DOI:10.25077/jrk.v12i1.364