Chronic Diarrhea and Neutropenia Not Associated with Pancreatic Insufficiency: A Non-Shwachman-Diamond Entity
Six children with chronic diarrhea and neutropenia, initially referred for evaluation of Shwachman-Diamond syndrome, were found to have no evidence of pancreatic insufficiency. All presented in the spring with a prodromal respiratory illness. Hematologic evaluation was normal except for iron deficie...
Saved in:
Published in | Journal of pediatric gastroenterology and nutrition Vol. 2; no. 3; pp. 559 - 562 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
Lippincott-Raven Publishers
01.08.1983
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Six children with chronic diarrhea and neutropenia, initially referred for evaluation of Shwachman-Diamond syndrome, were found to have no evidence of pancreatic insufficiency. All presented in the spring with a prodromal respiratory illness. Hematologic evaluation was normal except for iron deficiency anemia and neutropenia. Small intestinal biopsies of all children showed inflammation, consistent with chronic enteritis. The children were followed until growth returned to previous percentiles. Diarrhea and neutropenia resolved by 6-month follow-up, and there was no recurrence of the neutropenia at 1 year. |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0277-2116 1536-4801 |
DOI: | 10.1002/j.1536-4801.1983.tb08543.x |