Radiologic, Ultrasonic and pathological assessments of locally applied estrogen on promotion of experimentally induced tibial fracture healing in rats

The objective of the present study was to evaluate the ability of estrogen to promote induced tibial fracture healing in a rat model. The study was conducted on 14 albino rats divided into two equal groups (seven rats in each group). The first group considered as a control group. The second group wa...

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Bibliographic Details
Published inJournal of veterinary medical research Vol. 27; no. 1; pp. 37 - 51
Main Authors Kotb, M. M. A1, Ragab, G. A.2, Fathy, M. Z .2, Haggag, U.2, Nesreen. M. Safwat3
Format Journal Article
LanguageEnglish
Published Faculty of Veterinary Medicine, Beni-Suef University 01.06.2020
Subjects
albino rats; fracture; healing; pathological; radiological; ultrasonic
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Summary:The objective of the present study was to evaluate the ability of estrogen to promote induced tibial fracture healing in a rat model. The study was conducted on 14 albino rats divided into two equal groups (seven rats in each group). The first group considered as a control group. The second group was injected estradiol solution 0.1 mg/kg into the fracture gap. The progress of healing in each group was evaluated by clinical, radiography, ultrasonography and pathological examinations. The healing process was observed to be superior in the estrogen group compared to the control one. Estrogen was found to promote healing of injured bone and is suggested to be used in cases of complicated or delayed bone fracture.
ISSN:2357-0520
2357-0512
2357-0520
DOI:10.21608/jvmr.2020.69693