A molecular insight in the prevalence of odontogenic tumor
Odontogenic tumors (OT) encompass a diverse collection of lesions that ranges from hamartomas to benign and malignant neoplastic lesions of erratic aggressiveness. The progress and development of OT are influenced by variation of many kinds of genes and molecules. Genetic instability is a hallmark o...
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Published in | Journal of Advanced Clinical and Research Insights Vol. 3; no. 6; pp. 209 - 211 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Bangalore
Incessant Nature Science Publishers Private Limited
01.11.2016
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Subjects | |
Online Access | Get full text |
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Summary: | Odontogenic tumors (OT) encompass a diverse collection of lesions that ranges from hamartomas to benign and malignant neoplastic lesions of erratic aggressiveness. The progress and development of OT are influenced by variation of many kinds of genes and molecules. Genetic instability is a hallmark of cancer. This review illustrate a concurrent sketch of the recent updating of the molecular and genetic alterations linked with the growth and development of OT, including oncogenes, tumor-suppressor genes, oncoviruses, growth factors cell cycle regulators, apoptosis-related factors, regulators of tooth development, hard tissue-related proteins, cell adhesion molecules, matrixdegrading proteinases, factors of angiogenesis, and osteolytic cytokines. The logical and enhanced understanding of the molecular mechanism may provide newer thoughts for their recognition and administrate an improved prognosis of OT. |
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ISSN: | 2393-8625 2393-8625 |
DOI: | 10.15713/ins.jcri.140 |