Inhibitory Effect of Olive (Olea europaea) Leaves Extract on Candida Yeast Isolated from the Respiratory System of Human

• Published in: Tikrit Journal of Pure Science Vol. 30; no. 3; pp. 1 - 13
• Main Authors: Sami Farhan, Mohammed, Salwan Numan, Rand
• Format: Journal Article
• Language: English
• Published: Tikrit University 25.06.2025
• Subjects: Antifungals, Candida, Extract, Olive leaves, Respiratory system
• ISSN: 1813-1662; 2415-1726
• DOI: 10.25130/tjps.v30i3.1760

The laboratories of the Biology Department were used to conduct this investigation. at the College of Science - Tikrit University for the period from February 2024 to April 2024 and included the work of an aqueous and alcoholic extract of olive leaves. The study was conducted in two aspects, the first aspects is to show the effect of extracts (aqueous and alcoholic) of olive leaves using the diffusion method in the drilling, and the relationship was positive, i.e. whenever the higher the concentration of the extract, effect of its inhibitory becomes greater. The second aspects is to show the effect of antifungals on the yeasts used in the study. The results showed the effect of both the aqueous and alcoholic extracts at all concentrations. Candida albicanis yeast was more affected by the aqueous extract at a rate of inhibition diameter (16 mm), while Candida kefyr yeast was less affected by the aqueous extract at a rate of (12.2 mm). Candida glabrata yeast was more affected by the acetonic extract at a rate of (11.3 mm), while C.kyfer yeast was less affected by this extract at a rate of (6.5 mm). As for antifungals, a number of antifungals were used: Nystatin, Amphotericin, Clotrimazole, and Fluconazole. The antifungal Clotrimazole was the most effective, as it inhibited all the yeasts used in the study. The yeast C. glabrata was the most affected by this antifungal, with an inhibition diameter of (14 mm).