Hypotonia and Psychomotor Delay Revealing a Vitamin B12 Deficiency: About 2 Cases

Vitamin B 12 has important consequences for hematopoiesis and the central nervous system, its deficiency leads to clinical hematological, neurological and psychiatric manifestations. However, most infants with B12 deficiency are born to women with low vitamin B12 levels and have been exclusively bre...

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Published inScholars Journal of Medical Case Reports Vol. 11; no. 3; pp. 328 - 331
Main Authors Jounaid, F. Z., Baidi, H., Azitoune, S., Saghir, S., Abilkassem, R., Hassani, A., Kmari, M., Ourrai, A., Agader, A.
Format Journal Article
LanguageEnglish
Published 17.03.2023
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Summary:Vitamin B 12 has important consequences for hematopoiesis and the central nervous system, its deficiency leads to clinical hematological, neurological and psychiatric manifestations. However, most infants with B12 deficiency are born to women with low vitamin B12 levels and have been exclusively breastfed. An early diagnosis and treatment may prevent the progression of neurological damage to irreversible deficits. We report the case of two infants aged 6 months and 10 months, exclusively breastfed, with a significant psychomotor delay, and hypotonia. Physical examination confirmed the pallor, the axial hypotonia, biological examination revealed pancytopenia with a collapsed vitamin B12 level in both infants and both mothers.
ISSN:2347-9507
2347-6559
DOI:10.36347/sjmcr.2023.v11i03.020