Recent Progress on Exosomes in the Diagnosis of Prostate Cancer

Prostate cancer (Pca) is the second common cancer in men worldwide. Although prostate-specific antigen (PSA) screen can serve as a diagnostic marker in most of the patients with Pca, its diagnostic specificity is insufficient, and the false positive rate can result in unnecessary biopsy increasing p...

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Bibliographic Details
Published inAnnals of urologic oncology Vol. 6; no. 1; pp. 18 - 26
Main Authors Wang, Juanzi, Liu, Tianlong, Liu, Minna
Format Journal Article
LanguageEnglish
Published Asian Medical Press Ltd.(H.K.) 05.03.2023
Subjects
diagnosis
exosome
prostate cancer
tumor marker
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Summary:Prostate cancer (Pca) is the second common cancer in men worldwide. Although prostate-specific antigen (PSA) screen can serve as a diagnostic marker in most of the patients with Pca, its diagnostic specificity is insufficient, and the false positive rate can result in unnecessary biopsy increasing pain and treatment costs in patients. Exosomes are source for mRNA, microRNA, non-encoded RNA, protein, and lipids. In recent years, exosome are used for assessment of tumors and serve as tumor markers for early diagnosis and disease prognosis. This article highlights the application of exosomes in connection with diagnosis, treatment and prognosis of Pca.
ISSN:2617-7765
2617-7773
DOI:10.32948/auo.2023.03.14