ORAL VERRUCOUS PEMPHIGUS VEGETANS. A CASE REPORT

Pemphigus vegetans is a chronic mucocutaneous autoimmune blistering disease that can involve oral mucosa, whose behavior is normally benign. We present a case of a 50-year-old man with an unremarkable past medical history who smokes 20 cigarettes every day. For the last 3 months, he has complained o...

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Published inOral surgery, oral medicine, oral pathology and oral radiology Vol. 129; no. 1; pp. e61 - e62
Main Authors DE MENDOZA, IRENE LAFUENTE IBAÑEZ, PÉREZ, CARMEN PARRA, NAVARRO, JAVIER ALBERDI, DE PIEROLA, SANTIAGO FERNÁNDEZ, URIZAR, JOSÉ MANUEL AGUIRRE
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.01.2020
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Summary:Pemphigus vegetans is a chronic mucocutaneous autoimmune blistering disease that can involve oral mucosa, whose behavior is normally benign. We present a case of a 50-year-old man with an unremarkable past medical history who smokes 20 cigarettes every day. For the last 3 months, he has complained of pain on the gums. Clinical examination showed multiple white plaques on the buccal gingiva of all 4 quadrants, with a verrucous appearance, some of which had a reddish area. Incisional biopsies were performed of the lesions from the gingiva with clinical diagnosis of proliferative multifocal leukoplakia as well as a microbiologic culture intake. Histopathologic analysis, showing a verrucous epithelial hyperplasia with acantholysis, confirmed the diagnosis of verrucous pemphigus vegetans. Indirect immunofluorescence results for desmoglein 1 and 3 were negative. The patient remains under control after treatment with deflazacort and triamcinolone. This research was supported by a research group from UPV/EHU.
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2019.06.233